Use when working directly with the `esm` Python SDK, ESM3 or ESMC model IDs, Forge/Biohub inference clients, or ESMFold2 folding workflows.
---
name: esm
description: Use when working directly with the `esm` Python SDK, ESM3 or ESMC model IDs, Forge/Biohub inference clients, or ESMFold2 folding workflows.
license: MIT license
metadata: {"version": "1.1", "skill-author": "K-Dense Inc."}
---
# ESM: Evolutionary Scale Modeling
## Overview
ESM provides protein language models for understanding, generating, and designing proteins. Use this skill for current EvolutionaryScale/Biohub workflows: ESM3 for generative design, ESMC for representation learning and embeddings, hosted Forge/Biohub inference, and ESMFold2 all-atom structure prediction.
## Core Capabilities
### 1. Protein Sequence Generation with ESM3
Generate novel protein sequences with desired properties using multimodal generative modeling.
**When to use:**
- Designing proteins with specific functional properties
- Completing partial protein sequences
- Generating variants of existing proteins
- Creating proteins with desired structural characteristics
… load the full skill through Skill Me